3-[2-(MORPHOLIN-4-YL)ETHOXY]BROMOBENZENE
4-[2-(3-bromophenoxy)ethyl]morpholine
CAS: 435283-95-7
Molecular Formula: C12H16BrNO2
3-[2-(MORPHOLIN-4-YL)ETHOXY]BROMOBENZENE - Names and Identifiers
| Name | 4-[2-(3-bromophenoxy)ethyl]morpholine |
| Synonyms | 4-[2-(3-bromophenoxy)ethyl]morpholine 4-(2-(3-Bromophenoxy)ethyl)morpholine 4-[2-(3-BROMOPHENOXY)ETHYL]MORPHOLINE 1-[2-(3-BROMOPHENOXY)ETHYL]-MORPHOLINE Morpholine, 4-[2-(3-bromophenoxy)ethyl]- 3-[2-(MORPHOLIN-4-YL)ETHOXY]BROMOBENZENE |
| CAS | 435283-95-7 |
| InChI | InChI=1/C12H16BrNO2/c13-11-2-1-3-12(10-11)16-9-6-14-4-7-15-8-5-14/h1-3,10H,4-9H2 |
3-[2-(MORPHOLIN-4-YL)ETHOXY]BROMOBENZENE - Physico-chemical Properties
| Molecular Formula | C12H16BrNO2 |
| Molar Mass | 286.16 |
| Density | 1.358g/cm3 |
| Boling Point | 141 °C |
| Flash Point | 175.9°C |
| Vapor Presure | 1.39E-05mmHg at 25°C |
| Refractive Index | 1.547 |
3-[2-(MORPHOLIN-4-YL)ETHOXY]BROMOBENZENE - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Hazard Note | Corrosive |
3-[2-(MORPHOLIN-4-YL)ETHOXY]BROMOBENZENE - Introduction
4-[2-(3-bromophenoxy)ethyl]morpholine is an organic compound with the chemical formula C13H16BrNO2. It is a white to pale yellow solid, insoluble in water at room temperature and soluble in organic solvents such as ethanol and dimethylformamide.
4-[2-(3-bromophenoxy)ethyl]morpholine has analgesic and sedative effects, and is used as a precursor or intermediate of drugs. It is used in the pharmaceutical industry for the synthesis of other drugs, such as timolol (borolol).
The method of preparing 4-[2-(3-bromophenoxy)ethyl]morpholine includes the following steps:
1. 3-bromophenol is reacted with potassium hydroxide in ethanol to obtain potassium salt of 3-bromophenol.
2. morpholine and 3-bromophenol potassium salt are added in dimethylformamide to react to generate 4-[2-(3-bromophenoxy)ethyl]morpholine.
3. The reaction mixture was purified and crystallized to give the pure product.
Regarding safety information, 4-[2-(3-bromophenoxy)ethyl]morpholine is an organic compound that needs to be protected in laboratories and workplaces. It may be irritating to the eyes, skin and respiratory system and should be avoided. Wear personal protective equipment such as protective gloves, goggles and protective masks when using or handling the substance. When handling the compound, follow correct safety procedures and ensure that it is carried out under well-ventilated conditions. When storing and handling the compound, avoid contact with strong oxidants and flammable materials, avoid fire and high temperature. If not used or handled correctly, the substance may cause harm to humans and the environment. In order to ensure safety, it is recommended to operate under the guidance of professionals.
4-[2-(3-bromophenoxy)ethyl]morpholine has analgesic and sedative effects, and is used as a precursor or intermediate of drugs. It is used in the pharmaceutical industry for the synthesis of other drugs, such as timolol (borolol).
The method of preparing 4-[2-(3-bromophenoxy)ethyl]morpholine includes the following steps:
1. 3-bromophenol is reacted with potassium hydroxide in ethanol to obtain potassium salt of 3-bromophenol.
2. morpholine and 3-bromophenol potassium salt are added in dimethylformamide to react to generate 4-[2-(3-bromophenoxy)ethyl]morpholine.
3. The reaction mixture was purified and crystallized to give the pure product.
Regarding safety information, 4-[2-(3-bromophenoxy)ethyl]morpholine is an organic compound that needs to be protected in laboratories and workplaces. It may be irritating to the eyes, skin and respiratory system and should be avoided. Wear personal protective equipment such as protective gloves, goggles and protective masks when using or handling the substance. When handling the compound, follow correct safety procedures and ensure that it is carried out under well-ventilated conditions. When storing and handling the compound, avoid contact with strong oxidants and flammable materials, avoid fire and high temperature. If not used or handled correctly, the substance may cause harm to humans and the environment. In order to ensure safety, it is recommended to operate under the guidance of professionals.
Last Update：2024-04-09 20:02:46
![3-[2-(MORPHOLIN-4-YL)ETHOXY]BROMOBENZENE](http://res.chembk.com/assets/str/2d/4/43/435283-95-7.png)